Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. We comply with the HONcode standard for trustworthy health information -. The use of Pantothenic acids in supplements does vary greatly from person to person. However, many people have no side effects or only have minor side effects. You can buy pantothenic acid and pantethine as dietary supplements 2.According to NYU's Langone Medical Center, pantothenic acid has been suggested as an aid in the treatment of rheumatoid arthritis, for sports performance enhancement and in fighting stress 2.The list of suggested uses is even longer, according to MedlinePlus. This deficiency is rare. Use pantothenic acid as ordered by your doctor. Call your doctor or get medical Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Supplemental Uses. Pantothenic acid (also called vitamin B5) helps turn the food you eat into the energy you need. Nonetheless, it is generally used as a dietary supplement, first and foremost. Lowered food intake, body weight, insulin, glucose, and triglyceride levels, as well as decreased cholesterol and improvements in other parameters have been demonstrated with use of pantethine in animal experiments.9, 10, 11, 12, 13, 14, A review of pantethine's use as a nutraceutical option for the treatment of hypertriglyceridemia as well as a meta-analysis of pantethine's efficacy and tolerability covering 28 studies from 1966 to 2002 was published. [1] Tell your doctor about the allergy and Vitamin B5 deficiency is extremely rare in people as pantothenic acid is found in nearly … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Allergic contact dermatitis has been reported with topical use of dexpanthenol and panthenol cream.1, 38, 41 A meta-analysis from 1966 to 2002 recorded an adverse reaction rate of 1.4 per 100 subjects. An oral median lethal dose of 10 g/kg, resulting in respiratory failure, has been reported in mice.2, 36. biotin, multivitamin, ascorbic acid, calcium / vitamin d, Fish Oil. to make sure that it is safe for you to take pantothenic acid with all of your drugs and health problems. Pantothenic acid also plays a role in the production of coenzyme A, which is responsible for many biochemical reactions, including the synthesis and oxidation of fatty acids, as well as the uptake of drugs and toxins in the liver. The primary marketed supplemental form of pantothenic acid is calcium D-pantothenate (D-calcium pantothenate). The body uses it to breakdown carbohydrates, proteins and fats and turn them into glucose so the body can then use it for fuel. Signs of an allergic reaction, like rash; Store in a dry place. If your dose is different, do not change it unless your doctor tells you to do so. It is frequently included in various vitamin B-complex formulations. This vitamin is used to prevent or treat pantothenic acid (vitamin B5) deficiency. Treatment that was initiated pre-procedure improved mechanical properties of wound scars.39 Further studies are warranted. Chick antidermatitis factor was the name given to purified concentrates of this substance, as was vitamin B5, but these terms are now obsolete. Caution may be warranted with concomitant use of biotin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. It is also essential in producing, transporting, and releasing energy from fats. Pantothenic acid has been assigned US Food and Drug Administration (FDA) Pregnancy Category A (studies have failed to demonstrate risk). What do I need to tell my doctor BEFORE I take Pantothenic Acid? This breaks down fatty acids, triglycerides, and cholesterol in your body. Vitamin B5, also called pantothenic acid, is one of 8 B vitamins. Pantothenic acid is chemically unstable, hygroscopic, viscous oil, sensitive to acids, bases, and heat. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Clinical studies have used pantethine 600 to 1,200 mg/day for dyslipidemia, 200 to 300 mg/day for wound healing, and 1.5 g/day for exercise performance; typically, a dosage of 300 mg 3 times daily is recommended.15, 16, 37, 38, Pantothenic acid has been assigned US FDA Pregnancy Category A (ie, adequate, well-controlled studies have failed to demonstrate a risk to the fetus). In high doses, pantothenic acid may inhibit the absorption of biotin produced by the microflora in the large intestine. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The name pantothenic acid is derived from the Greek pantothen, meaning "from all sides" or "everywhere." Pantothenic acid deficiency is rare. There may be drug take-back programs in your area. Dexpanthenol, considered a provitamin form, is the corresponding alcohol of pantothenic acid. This information is not specific medical advice and does not replace information you receive from your health care provider. This is only a brief summary of general information about this product. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Your body needs vitamin B5 to. Knowledge of pantothenic acid resulted from experimentation on microorganisms and chicks. B5 is another of the B family. Despite positive findings in rodent studies, little positive clinical data exist regarding the use of pantothenic acid in the condition or growth of human hair. You must check This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Uses Pantothenic acid, also called vitamin B5, is a water-soluble vitamin involved in the Kreb's cycle of energy production and is needed to make the neurotransmitter acetylcholine. Pantothenic acid concentrations in human breast milk weakly correspond with maternal intake.2, 36, None well documented. Pantothenic acid is optically active, with maximum biological activity only in the D-form. In a 1998 review, the Institute of Medicine did not set a tolerable upper intake level for pantothenic acid because reports of adverse effects are lacking. Clinical studies have used pantothenic acid 600 to 1,200 mg/day for dyslipidemia. any drug without checking with your doctor. Skin & Hair Care. We comply with the HONcode standard for trustworthy health information -, http://www.ncbi.nlm.nih.gov/books/NBK114311/. In the body, pantothenic acid is converted to the related chemical pantethine, the biologically active form. Symptoms include fatigue, apathy, sleep disturbances, GI symptoms, numbness and paresthesias, muscle cramps, and hypoglycemia.1, 2, 3 Pantothenic acid was given to prisoners of war in Asia during World War II to alleviate Grierson-Gopalan syndrome, also known as burning feet syndrome, now essentially unknown and thought to be due to malnutrition.1, 2. The RDA during pregnancy and lactation is slightly higher, at 6 and 7 mg daily, respectively. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. It can also be applied to the skin to relieve itchiness and promote healing from skin conditions, such as: eczema insect bites poison ivy diaper rash The vitamin circulates in plasma as such; the conversion to CoA takes place after it is taken up by cells. Two studies (n = 67) evaluated the ascorbid acid/pantothenic acid combination in patients undergoing surgical resection for tattoo removal. You will need to talk about any risks to your baby. Pantothenic acid (vitamin B-5) is one of the eight B vitamins. For more details, see our health professional fact sheet on Pantothenic Acid.. What is pantothenic acid and what does it do? Keep all drugs in a safe place. Pantothenic acid is frequently used in combination with other B vitamins in vitamin B complex formulations. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Another example, published in the International Journal for Vitamin and Nutritional Research, found that higher quantities of pantothenate enhance wound healing. Follow all instructions closely. It can also be used in supplements to treat Vitamin B5 deficiencies. This includes your doctors, nurses, pharmacists, and dentists. Clinical studies are limited. Liquid preparations of pantothenic acid are commercially available as D-pantothenyl alcohol or panthenol.1, 2. If you are allergic to pantothenic acid; any part of pantothenic acid; or any other drugs, foods, or substances. Do not flush down a toilet or pour down a drain unless you are told to do so. Read all information given to you. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. No benefit was seen for exercise performance, muscle coenzyme A levels, or fuel selection.40, The US RDA for pantothenic acid in nutritional supplements and foods is age dependent and ranges from 0.2 mg/kg in infants to 5 mg in adults. Pantothenic acid is optically active, with maximum biological activity only in the D-form. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. However, larger clinical studies are warranted in more diverse populations before a definitive role for pantethine can be defined.15, 16, Limited animal experiments have studied the role of pantethine in lens opacification and light scattering during cataract formation. Like the other complex B vitamins, vitamin B-5 plays a vital role in helping the human body maintain good health. Research suggests that pantethine prevents the formation of insoluble proteins in the lens.17, 18, 19, 20, A study evaluated the effect of dexpanthenol 5% following phototherapeutic keratectomy. Pantothenic Acid, which is also known as pantothenate, or simply vitamin B5, is a water soluble vitamin in the B vitamin family. You will need to talk about the benefits and risks of using pantothenic acid The dose of this medicine will be different for different patients. Dexpanthenol as a pastille and as a spray has been evaluated in small clinical trials for wound healing in postoperative tonsillectomy, endotracheal intubation, and endoscopic sinus surgery.25, 26, 27 Increased hydration due to dexpanthenol may explain the positive effects, or a possible increase in the number of dermal fibroblasts.2 An evidence-based review of the benefit of vitamin supplements for wound healing identified data on the combination of ascorbic acid and pantothenic acid for surgical wounds. Throw away unused or expired drugs. Calcium pantothenate uses Pantothenic acid is frequently used in combination with other B vitamins in vitamin B complex formulations. Pantothenic acid is used in the synthesis of CoA via a five-step process that requires pantothenic acid, four molecules of ATP and cysteine (see figure). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. The following information includes only the average doses of this medicine. This is a reader-friendly overview of Pantothenic Acid. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. A tolerable upper intake level for pantothenic acid has not been set because reports of adverse effects are lacking. 10 In addition to its uses, pantothenic acid may also provide the … This information relates to an herbal, vitamin, mineral or other dietary supplement. Panthenol is widely used in clinical practice for the improvement of wound healing … These B vitamins, often referred to as B complex vitamins, also help the body use fats and protein. You should talk with your health care provider for complete information about the risks and benefits of using this product. Avoid use if hypersensitivity to pantothenic acid exists. Medically reviewed by Drugs.com. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Tell all of your health care providers that you take pantothenic acid. By the microflora in the large intestine median lethal dose of 10 g/kg for mice has been in. Cholesterol in your area Category C. None well documented used in combination with other B vitamins the... Derived from the Greek pantothen, meaning `` from all sides '' or `` everywhere. this breaks fatty... ; or any other part of pantothenic acids in supplements to treat acid. 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